US Airways is an American low-cost carrier and one of the largest airlines in the United States, based in Tempe, Arizona. Together with its America West Airlines affiliate, US Airways (which also comprises regional / commuter airlines US Airways Shuttle and US Airways Express), operate scheduled passenger services to 240 destinations in 26 countries across North America, Central America, the Caribbean, Hawaii and Europe. Some of the major destinations served by US Airways include London, Frankfurt, Athens, Nassau, Milan, Madrid, Vancouver, Cozumel, San Juan and Maui. US Airways maintains major hubs in Charlotte, Philadelphia, Phoenix and Las Vegas.